PHARMACEUTICAL GRANULATION AND COMPRESSION

TRAINING PHARMACEUTICAL GRANULATION AND COMPRESSION

 

DESCRIPTION TRAINING PHARMACEUTICAL GRANULATION AND COMPRESSION

Granulation and compression are two very important processes that are carried out extensively by most pharmaceutical companies. However, the theory of granulation is little understood and the selection of a particular machine and granulation method, is often done on the basis of tradition, rather than by using strict scientific or cost-benefit criteria. The basic techniques have changed dramatically in recent years and granulation for controlled release, extrusion, spheronisation, fluidization techniques, spray drying, melt extrusion, oral dispersion technology and roller compaction are new technologies that are increasingly being used in modern pharmaceutical production, which exhibit many advantages over previously available techniques. As with granulation, compression is also little understood and why some materials/formulations will compress well whilst others compact with difficulty, is slowly being elucidated. The Course will examine current granulation and compression theory and practice. Emphasis will be made as to how this theory and practice relates to current pharmaceutical development and production, with special reference to the machinery used. Scale-Up, Transfer Technology and SUPAC will also be addressed. A particular feature of the Course will be the workshop on new melt extrusion technology. 

OBCECTIVES

The aims of the Course are to provide a comprehensive and sound understanding of the theory and practice of tablet granulation and compression and to appreciate the various processes batch or continuous, that are available. The importance of the granulation process in producing good quality tablets will be emphasized. The modern techniques of extrusion, spheronisation, powder layering, roller compaction, fluid-bed processing, spray drying, melt extrusion, oral dispersion technology and tablet compression will be covered. The Course will be taught primarily by industrial scientists who have been closely involved with investigating these granulation and compression processes and thus a pragmatic approach will be adopted throughout.

SUMMARY OF KEY BENEFITS

At the end of the Course participants will have:

  • An understanding of the fundamental principles of granulation and the advantages, disadvantages and potential of the various granulation, layering, spray drying, oral dispersion, extrusion and spheronisation methods
  • An understanding of the techniques and processes available for granulation in relation to controlled release products
  • Detailed knowledge on current ideas and thoughts on Scale-Up, Transfer Technology and SUPAC
  • An appreciation of some of the compression problems that can arise and how they can be overcome
  • A knowledge of the factors that should be taken into consideration when selecting granulation and compression equipment

COURSE CONTENTS

  1. Methods and Reasons for Granulating
  2. Excipients
  3. Properties of Granules
  4. Granulation for Controlled Release
  5. High Speed Granulation and End-Point Control
  6. Integrated Mixer-Granulator Dryers
  7. Fluid Bed Granulation
  8. Layering
  9. Spray Drying
  10. Pellet Manufacture
  11. Extrusion and Spheronization
  12. Hot Melt Extrusion
  13. Roller Compaction
  14. Compression Theory
  15. Compression Machinery
  16. Compaction Simulators
  17. Tabletting and Tooling Problems
  18. Oral Dispersion Tabletting Technology
  19. Scale-Up, Transfer Technology and Supac

WHO SHOULD ATTENDS

All who are working in pharmaceutical research, formulation, development, production, QA/QC and registration who require a sound understanding of the various granulation and compression methods and who wish to appreciate some of the advantages of the newer methods of granulation, spheronisation, roller compaction, layering, melt extrusion and compression that are now available.

INSTRUKTUR PELATIHAN

Ir. Chandra Wahyu Purnomo

Fasilitas TRAINING PHARMACEUTICAL GRANULATION AND COMPRESSION

  1. Lokasi Training di Hotel Bintang 3-5
  2. Sertifikat Training
  3. Modul Materi (Hard Copy & Soft Copy)
  4. Flashdisk
  5. Training Kit (Co-Card, Bolpoin, & Buku Catatan)
  6. Souvenir Eksklusif
  7. 1x Makan Siang dan 2x Coffee Break (Jam 10:00 & 14:00)
  8. Penjemputan Bandara – Hotel (Pulang-Pergi selama pelatihan)

Biaya dan Lokasi TRAINING PHARMACEUTICAL GRANULATION AND COMPRESSION

  • Yogyakarta : Rp 8.800.000,- / Peserta
  • Bandung : Rp 8.800.000,- / Peserta
  • Jakarta : Rp 8.800.000,- / Peserta
  • Surabaya : Rp 8.800.000,- / Peserta
  • Malang : Rp 8.800.000,- / Peserta
  • Semarang : Rp 8.800.000,- / Peserta
  • Solo : Rp 8.800.000,- / Peserta
  • Bali : Rp 7.000.000,- / Peserta (Minimal 2 peserta)
  • Lombok: Rp 7.400.000,- / Peserta (Minimal 2 peserta)

Keterangan

  • Biaya diatas jika 1 perusahaan hanya mengirimkan 1 peserta.
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  • Jumlah peserta, jadwal training dan lokasi training dapat menyesuaikan permintaan.
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